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POLUPI Tab. 3
2226BC

POLUPI Tab.

DOH PM 043335


< COMPOSITION >
Each tablet contains:
Propylthiouracil .................50mg

< ACTIONS >
Propylthiouracil is used to treat hyperthyroidism (a condition that occurs when the thyroid gland produces too much thyroid hormone, speeding the body's metabolism, and causing certain symptoms) in adults and children 6 years of age or older. Propylthiouracil is in a class of medications called antithyroid agents. It works by stopping the thyroid gland from making thyroid hormone.

< INDICATION >
 For the treatment of hyperthyroidism.

< DOSAGE >
Hyperthyroidism:
300-450 mg/day PO divided q8hr initially (may require up to 600-900 mg/day). Maintenance: 100-150 mg/day divided q8hr.
Thyrotoxic Crisis (Off-label):
Initial 200-300 mg PO q4-6hr initially on Day 1 (may require 800-1200 mg/day), then reduce gradually; some practitioners propose an initial dose of 600-1000 mg with gradual dose reduction after initial response.
Maintenance: 100-150 mg/day PO divided q8-12hr.
Graves Disease:
50-150 mg PO q8hr initially.
Maintenance: 50 mg PO q8-12hr for up to 12-18 months; then taper and discotinue if euthyroidism restored (TSH) is normal.

< PACKAGE >
1000'S/PTP/box
ANTITHYROID AGENT 1244954